Professor and Chair, Department of Biomedical Engineering
Phone: (514) 398-7676
740 Dr Penfield Ave, Room 6206
Montréal, Québec, Canada, H3A 0G1
From: Neuchâtel, Switzerland
Biography: David stayed as a visiting scientist at the National Metrology Institute of Japan in Tsukuba from 1997-1998. He conducted his PhD research at the IBM Zurich Research Laboratory from 1999-2002. He then pursued his studies as a Post-doc first at IBM Zurich until 2004, and then one year at the Swiss Federal Institute of Technology in Zurich (ETH).David started as an assistant professor in the Biomedical Engineering Department of McGill University in 2005, was promoted to associate professor with tenure in 2011, and became a full professor in 2016. As of early 2018, David serves as departmental chair of the Biomedical Engineering Department at McGill University.
David’s current interests are in the miniaturization and integration in biology and medicine, which includes the engineering and utilization of novel micro and nanotechnologies for manipulating, stimulating and studying oligonucleotides, proteins, cells, and tissues. The emerging field of nanobiotechnology, in a broad sense, is the most exciting to David, and is also key to tackle some of the major challenges in biology and medicine, for example identifying novel biomarkers for early disease diagnosis and developing low-cost point-of-care diagnostics.
The future of biological and biomedical research is small in scale, but immense in impact. We believe in the power of human creativity and ingenuity to advance our understanding of human health and to cure disease, and aspire to develop ground-breaking, transformative micro and nanobioengineering technologies for bioanalysis, precision medicine, tissue engineering and organ-on-a-chip. Our research is highly collaborative and interdisciplinary, conducted by a team of research associates, post-doctoral fellows, graduate and undergraduate students from all areas of science and engineering.
- Normandeau, F, Ng, A, Beaugrand, M, Juncker, D. Spatial Bias in Antibody Microarrays May Be an Underappreciated Source of Variability. ACS Sens. 2021;6 (5):1796-1806. doi: 10.1021/acssensors.0c02613. PubMed PMID:33973474 .
- Dlamini, M, Kennedy, TE, Juncker, D. Combinatorial nanodot stripe assay to systematically study cell haptotaxis. Microsyst Nanoeng. 2020;6 :114. doi: 10.1038/s41378-020-00223-0. PubMed PMID:33365138 PubMed Central PMC7735170.
- Paquet-Mercier, F, Juncker, D, Bergeron, S. Precise Chip-to-Chip Reagent Transfer for Cross-Reactivity-Free Multiplex Sandwich Immunoassays. Methods Mol Biol. 2021;2237 :141-149. doi: 10.1007/978-1-0716-1064-0_12. PubMed PMID:33237415 .
- Bastien, JP, Fekete, N, Beland, AV, Lachambre, MP, Laforte, V, Juncker, D et al.. Closing the system: production of viral antigen-presenting dendritic cells eliciting specific CD8+ T cell activation in fluorinated ethylene propylene cell culture bags. J Transl Med. 2020;18 (1):383. doi: 10.1186/s12967-020-02543-1. PubMed PMID:33036618 PubMed Central PMC7547414.
- Goyette, PA, Boulais, É, Normandeau, F, Laberge, G, Juncker, D, Gervais, T et al.. Microfluidic multipoles theory and applications. Nat Commun. 2019;10 (1):1781. doi: 10.1038/s41467-019-09740-7. PubMed PMID:30992450 PubMed Central PMC6467910.
- Zimny, P, Juncker, D, Reisner, W. Hydrogel droplet single-cell processing: DNA purification, handling, release, and on-chip linearization. Biomicrofluidics. 2018;12 (2):024107. doi: 10.1063/1.5020571. PubMed PMID:30867855 PubMed Central PMC6404942.
- Munzar, JD, Ng, A, Juncker, D. Duplexed aptamers: history, design, theory, and application to biosensing. Chem Soc Rev. 2019;48 (5):1390-1419. doi: 10.1039/c8cs00880a. PubMed PMID:30707214 .
- Hernández-Castro, JA, Li, K, Daoud, J, Juncker, D, Veres, T. Two-level submicron high porosity membranes (2LHPM) for the capture and release of white blood cells (WBCs). Lab Chip. 2019;19 (4):589-597. doi: 10.1039/c8lc01256c. PubMed PMID:30648711 .
- Clancy, KFA, Dery, S, Laforte, V, Shetty, P, Juncker, D, Nicolau, DV et al.. Protein microarray spots are modulated by patterning method, surface chemistry and processing conditions. Biosens Bioelectron. 2019;130 :397-407. doi: 10.1016/j.bios.2018.09.027. PubMed PMID:30253928 .
- Dagher, M, Kleinman, M, Ng, A, Juncker, D. Ensemble multicolour FRET model enables barcoding at extreme FRET levels. Nat Nanotechnol. 2018;13 (10):925-932. doi: 10.1038/s41565-018-0205-0. PubMed PMID:30061659 .